Child Neurology: A Case of <i>FHL1</i>-Related Disease Presenting as Inflammatory Myopathy
نویسندگان
چکیده
Background and objective Acute ischemic stroke is a potentially devastating condition leading cause of morbidity mortality, affecting an estimated 800 000 people per year in the USA. The natural history untreated or unrevascularized large vessel occlusions acute patients results mortality rates approaching 30%, with only 25% achieving good neurologic outcomes at 90 days. Recently, data have demonstrated that early endovascular recanalization better than medical therapy alone. However, majority these studies were treated stent retriever based approach. purpose COMPASS to evaluate whether direct aspiration first pass (ADAPT) approach non-inferior functional those as firstline (SRFL) Materials methods All who meet inclusion exclusion criteria consent participate will be enrolled participating centers. Treatment randomly assigned by central web system 1:1 manner treatment either ADAPT SRFL thrombectomy. Statistical methodology prespecified details available statistical analysis plan. Results trial recently completed enrollment, collection/verification ongoing. final made on completion enrollment follow-up. Conclusions This paper design trial, randomized, blinded adjudicator, concurrent, controlled approaches order outcome. Trial registration number NCT02466893, Results.
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ژورنال
عنوان ژورنال: Neurology
سال: 2021
ISSN: ['0028-3878', '1526-632X']
DOI: https://doi.org/10.1212/wnl.0000000000011320